with flowcytometry, cytogenetic and molecular biology findings
Novartis IBA FM MU

Autoimmune haemolytic anaemia with cold antibodies

PB MGG (200×)

Marked agglutination of erythrocytes – due to the presence of cold antibodies – makes description of the blood smear impossible.

BM MGG (200×)

Erythropoiesis predominates in this cell-rich smear, forming smaller islets in some places (left lower quadrant).

PB MGG (1000×)

Numerous erythroblasts of different ages, some of them are macrocytic, other are normocytic (erythropoiesis is of macro-normoblastic character). A promyelocyte is marked by a yellow arrow, a neutrophilic myelocyte is marked by a red arrow, band cells are marked by cyan arrows, and a segmented eosinophil is marked by a black arrow.

PB MGG (1000×)

Numerous erythroblasts of different ages, most of them are macrocytic (erythropoiesis is of macroblastic character). A neutrophilic myelocyte is marked by a red arrow, a metamyelocyte is marked by a cyan arrow, and a segmented neutrophil is marked by a green arrow.

Atlas of Haematological Cytology [online]. 2016 [cit. 2024-4-25]. Available from WWW: http://www.leukemia-cell.org/atlas.

2024 CELL - Atlas of Haematological Cytology | site map